[HTML][HTML] Gene therapy for cardiovascular disease: basic research and clinical prospects

G Cao, X Xuan, R Zhang, J Hu, H Dong - Frontiers in cardiovascular …, 2021 - frontiersin.org
… as an advanced version of non-integrated gene-replacement … and promising targets of
atherosclerosis gene therapy. The … of common delivery vectors or methods for gene therapy were …

Gene therapy for the heart lessons learned and future perspectives

A Cannatà, H Ali, G Sinagra, M Giacca - Circulation research, 2020 - Am Heart Assoc
… , effectively advanced to deliver the desired treatment from … The birth of gene therapy for
cardiovascular disorders in the … shows 3 current gene therapy approaches targeted to cardiac

Gene therapy for ischaemic heart disease and heart failure

H Korpela, N Järveläinen, S Siimes… - Journal of Internal …, 2021 - Wiley Online Library
… the current status and future developments in this field. … targets, improved vectors and
delivery methods in the last decade has made gene therapy a realistic option for treating heart

Gene therapy and gene correction: targets, progress, and challenges for treating human diseases

MR Cring, VC Sheffield - Gene therapy, 2022 - nature.com
cardiovascular diseases with genetic etiologies, gene therapy can also be utilized in cases
of cardiovascular … There are many methods to deliver gene therapy and gene correction …

Targeted delivery of therapeutic agents to the heart

S Sahoo, T Kariya, K Ishikawa - Nature Reviews Cardiology, 2021 - nature.com
vector is increasingly being used for ex vivo gene delivery. … gene therapy for the treatment
of non-cardiac diseases has … targeted delivery to the heart might be required to advance

[HTML][HTML] Applications and developments of gene therapy drug delivery systems for genetic diseases

X Pan, H Veroniaina, N Su, K Sha, F Jiang… - Asian journal of …, 2021 - Elsevier
… the gene therapy drugs and their current application progress… reporter gene assay confirmed
that miR-218 targeted the … miRNA can treat cardiovascular diseases by regulating heart

[HTML][HTML] Gene therapy developments for Pompe disease

Z Unnisa, JK Yoon, JW Schindler, C Mason, NP van Til - Biomedicines, 2022 - mdpi.com
… In this review, we highlight gene therapy developments, in particular, AAV and LV HSPC-…
Muscle Directed Delivery Gene therapy targeting muscle could directly correct the affected …

The horizon of gene therapy in modern medicine: advances and challenges

B Arjmand, B Larijani, M Sheikh Hosseini… - Cell Biology and …, 2020 - Springer
gene therapy in overcoming some of these limitations, it still faces with complexities such as
substantial barriers to delivery of the vector, targeting … for immune dysfunction, heart disease, …

From traditional pharmacological towards nucleic acid-based therapies for cardiovascular diseases

U Landmesser, W Poller, S Tsimikas… - European heart …, 2020 - academic.oup.com
therapeutic targets suggested to be causal for CVD; (ii) there is a substantial recent progress
in delivery, … for non-cardiac monogenic diseases and LDL receptor gene therapy is currently …

Research Progress of nucleic acid delivery vectors for gene therapy

Y Jiao, ZL Xia, LJ Ze, H Jing, B Xin, S Fu - Biomedical microdevices, 2020 - Springer
Cardiac gene therapy using an AAV as a vector is becoming a new platform for treating and
even curing currently intractable heart disease. … platform for targeted, intelligent delivery and …